GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs1577917 | 1 | rs1857964 | chr6:86635994 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.48 | 2.8E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs1857965 | chr6:86630776 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -9.01 | 9.54E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs10461617 | 1 | rs1862619 | chr5:56098256 | C5orf35 | chr5:56205103-56213010:+ | 0.65 | 9.62 | 8.98E-20 | Type 2 diabetes |
| BLCA | cis | rs2243480 | 1 | rs186378 | chr7:65582058 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.95 | 1.13E-6 | Diabetic kidney disease |
| BLCA | cis | rs10935120 | 1 | rs1863913 | chr3:134200205 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.47 | 5.37E-13 | Height |
| BLCA | cis | rs7714584 | 1 | rs1863998 | chr5:150271753 | LOC134466 | chr5:150310000-150326146:- | 0.44 | 5.72 | 2.14E-8 | Crohn's disease |
| BLCA | cis | rs11051970 | 1 | rs1872829 | chr12:32535100 | FGD4 | chr12:32638906-32798982:+ | -0.33 | -5.34 | 1.6E-7 | Response to tocilizumab in rheumatoid arthritis |
| BLCA | cis | rs2243480 | 1 | rs1873494 | chr7:65649899 | CCT6P1 | chr7:65216092-65228661:+ | -0.35 | -4.71 | 3.52E-6 | Diabetic kidney disease |
| BLCA | cis | rs10935120 | 1 | rs1874883 | chr3:134205071 | ANAPC13 | chr3:134196547-134204865:- | 0.5 | 8.05 | 1.03E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs1874883 | chr3:134205071 | CEP63 | chr3:134204575-134293852:+ | 0.25 | 4.42 | 1.28E-5 | Height |
| BLCA | cis | rs703842 | 1 | rs1875124 | chr12:58196802 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.37 | 1.6E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs1875124 | chr12:58196802 | TSFM | chr12:58176536-58191367:+ | -0.38 | -6.72 | 6.57E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs1875124 | chr12:58196802 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -3.95 | 9.44E-5 | Multiple sclerosis |
| BLCA | cis | rs10935120 | 1 | rs1880376 | chr3:134270347 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs1880376 | chr3:134270347 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |